Abstract
The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 years there have been cases of chronic HEV hepatitis, mainly in immunosuppressed patients. Here we review the known data of chronic hepatitis E in terms of evolution and treatment.
Copyright © 2011 Elsevier España, S.L. All rights reserved.
MeSH terms
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Africa / epidemiology
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Americas / epidemiology
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Animals
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Antiviral Agents / therapeutic use
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Asia / epidemiology
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Chronic Disease
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Endemic Diseases
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Europe / epidemiology
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Food Contamination
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Genotype
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Hepatitis E virus / classification
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Hepatitis E virus / genetics
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Hepatitis E virus / immunology
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Hepatitis E virus / isolation & purification
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Hepatitis E* / drug therapy
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Hepatitis E* / epidemiology
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Hepatitis E* / prevention & control
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Hepatitis E* / transmission
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Hepatitis E* / virology
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Humans
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Immunocompromised Host
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Meat / virology
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Transfusion Reaction
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Viral Hepatitis Vaccines
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Zoonoses
Substances
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Antiviral Agents
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Viral Hepatitis Vaccines