Abstract
We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anti-Infective Agents / blood*
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Anti-Infective Agents / pharmacokinetics*
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Anti-Infective Agents / therapeutic use
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Baths
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Child
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Child, Preschool
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Chlorhexidine / analogs & derivatives*
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Chlorhexidine / blood
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Chlorhexidine / pharmacokinetics
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Chlorhexidine / therapeutic use
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Female
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Humans
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Infant
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Limit of Detection
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Male
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Skin Absorption*
Substances
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Anti-Infective Agents
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chlorhexidine gluconate
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Chlorhexidine