Abstract
A case of primary low-grade pulmonary lymphoma is described. The histologic features conformed to those laid down by Saltzstein for a diagnosis of "pseudolymphoma." However, the immunocytochemical and molecular investigations confirmed the tumor to be a low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). Cytogenetic studies revealed an abnormal karyotype with a translocation t(1;14). This is the first reported case of an abnormal karyotype in a case of a lymphoma of MALT.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens, Differentiation / metabolism
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Antigens, Differentiation, B-Lymphocyte / metabolism
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Antigens, Neoplasm / metabolism
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Cell Adhesion Molecules / metabolism
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Chromosomes, Human, Pair 1
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Chromosomes, Human, Pair 14
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DNA, Neoplasm / genetics
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Female
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Humans
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Immunoglobulin lambda-Chains / metabolism
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Immunohistochemistry
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Karyotyping
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Lung Neoplasms / genetics
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Lung Neoplasms / metabolism
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Lung Neoplasms / pathology*
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Lymphoma, B-Cell / genetics
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Lymphoma, B-Cell / metabolism
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Lymphoma, B-Cell / pathology*
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Middle Aged
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Neprilysin
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Receptors, Complement / metabolism
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Receptors, Complement 3d
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Translocation, Genetic / genetics
Substances
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Antigens, Differentiation
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Antigens, Differentiation, B-Lymphocyte
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Antigens, Neoplasm
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Cell Adhesion Molecules
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DNA, Neoplasm
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Immunoglobulin lambda-Chains
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Receptors, Complement
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Receptors, Complement 3d
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Neprilysin