Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist

J Med Chem. 1990 Dec;33(12):3122-4. doi: 10.1021/jm00174a002.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Apomorphine / analogs & derivatives*
  • Apomorphine / chemical synthesis
  • Apomorphine / chemistry
  • Apomorphine / metabolism
  • Cell Membrane / metabolism
  • Corpus Striatum / metabolism
  • Molecular Structure
  • Rats
  • Receptors, Dopamine / metabolism*
  • Receptors, Dopamine D1
  • Receptors, Dopamine D2
  • Structure-Activity Relationship

Substances

  • Receptors, Dopamine
  • Receptors, Dopamine D1
  • Receptors, Dopamine D2
  • 2-fluoro-N-n-propylnorapomorphine
  • Apomorphine