Introduction: Itraconazole is an azole derivative used for the treatment of aspergillosis. Cardiac failure is a rare complication of treatment. Most cases occur in patients with cardiovascular risk factors, or taking multiple medications, and a causal relationship is not well-established.
Case report: We report the case of a patient, without cardiovascular risk factors, presenting with cardiac failure during treatment with itraconazole. Pre-treatment stress testing and echocardiography were normal. Resolution was complete without sequelae.
Conclusion: Cardiac failure can occur in association with itraconazole despite normal cardiological investigations before treatment.
Copyright © 2011 SPLF. Published by Elsevier Masson SAS. All rights reserved.