A new strategy improves assembly efficiency of DNA mono-modified gold nanoparticles

Tao Zhang; Ping Chen; Yawei Sun; Yongzheng Xing; Yang Yang; Yuanchen Dong; Lijin Xu; Zhongqiang Yang; Dongsheng Liu

doi:10.1039/c1cc11337b

A new strategy improves assembly efficiency of DNA mono-modified gold nanoparticles

Chem Commun (Camb). 2011 May 28;47(20):5774-6. doi: 10.1039/c1cc11337b. Epub 2011 Apr 15.

Authors

Tao Zhang¹, Ping Chen, Yawei Sun, Yongzheng Xing, Yang Yang, Yuanchen Dong, Lijin Xu, Zhongqiang Yang, Dongsheng Liu

Affiliation

¹ Key Laboratory of Organic Optoelectronics & Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, PR China.

PMID: 21494746
DOI: 10.1039/c1cc11337b

Abstract

We report a new strategy to prepare DNA mono-modified gold nanoparticles (AuNPs). By adding a short rigid duplex proximal to the AuNPs, the assembly efficiency of DNA mono-modified AuNPs with Y-shaped DNA could be improved nearly 6-fold.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA, Single-Stranded / chemistry*
Electrophoresis, Agar Gel
Gold / chemistry*
Metal Nanoparticles / chemistry*
Thioctic Acid / chemistry

Substances

DNA, Single-Stranded
Thioctic Acid
Gold