Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology

Prog Brain Res. 1990:82:215-23. doi: 10.1016/s0079-6123(08)62607-2.

Authors

S J Richards¹, J J Waters, D C Rogers, F L Martel, D R Sparkman, C L White, K Beyreuther, C L Masters, S B Dunnett

Affiliation

¹ MRC Molecular Genetics Unit, Addenbrooke's Hospital, Cambridge, England, UK.

PMID: 2149769
DOI: 10.1016/s0079-6123(08)62607-2

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alzheimer Disease / etiology
Alzheimer Disease / pathology
Amyloid beta-Peptides / analysis
Amyloidosis / etiology*
Amyloidosis / pathology
Animals
Brain Tissue Transplantation / pathology*
Disease Models, Animal
Down Syndrome / complications
Fetal Tissue Transplantation / pathology*
Frontal Lobe
Hippocampus / pathology
Hippocampus / transplantation*
Mice
Mice, Mutant Strains
Neurofibrils / pathology*
Trisomy*

Substances

Amyloid beta-Peptides