Abstract
Amino acid-derived propargylic amides are cyclised in a one-pot, Au(III)-catalysed operation to yield 5-bromomethyl oxazoles. These compounds are further elaborated to bis-heterocycles, dipeptide mimics and more.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Amides / chemistry
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Amino Acids / chemistry*
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Catalysis
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Cyclization
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Gold / chemistry*
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Molecular Structure
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Oxazoles / chemical synthesis*
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Oxazoles / chemistry
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Stereoisomerism
Substances
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Amides
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Amino Acids
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Oxazoles
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Gold