A comparative infection study of pigeon and avian paramyxovirus type 1 viruses in pigeons: evaluation of clinical signs, virus shedding and seroconversion

Avian Pathol. 2011 Apr;40(2):125-30. doi: 10.1080/03079457.2010.542131.

Abstract

The pathogenesis of pigeon paramyxovirus type 1 (PPMV-1) isolate AV324/96 and of its recombinant derivative, rgAV324, was studied in pigeons. For comparison, the virulent chicken virus FL-Herts, which is a recombinant derivative of strain Herts/33, was also included. After inoculation by the combined intraocular, intranasal and intratracheal route, clinical signs, virus shedding and serological responses were examined. Clinical signs were observed only in the FL-Herts-infected group. All virus-inoculated pigeons had positive tracheal swabs until 5 days post infection. However, only the AV324/96-infected and rgAV324-infected birds, and not the FL-Herts-infected birds, shed virus in the cloaca. The AV324/96-infected pigeons showed higher mean antibody titres than the rgAV324-infected birds, whereas the antibody titres of the FL-Herts-infected group were rather low. The results show that the pigeon strain AV324 is not virulent for pigeons, but underlines the potential risk of poultry becoming infected by PPMV-1 shed by non-symptomatic pigeons.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Viral / biosynthesis
  • Antibodies, Viral / blood
  • Chickens / virology
  • Cloaca / virology
  • Columbidae / virology*
  • Newcastle Disease / immunology
  • Newcastle Disease / pathology
  • Newcastle Disease / virology*
  • Newcastle disease virus / isolation & purification
  • Newcastle disease virus / pathogenicity*
  • Newcastle disease virus / physiology*
  • Poultry / virology
  • Poultry Diseases / immunology
  • Poultry Diseases / pathology
  • Poultry Diseases / virology*
  • Trachea / virology
  • Virulence
  • Virus Shedding / physiology*

Substances

  • Antibodies, Viral