Mechanism of action of the cytotoxic macrolides amphidinolide X and J

Chembiochem. 2011 May 2;12(7):1027-30. doi: 10.1002/cbic.201100042. Epub 2011 Apr 15.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Dose-Response Relationship, Drug
  • Drug Screening Assays, Antitumor
  • Humans
  • Macrolides / chemistry
  • Macrolides / pharmacology*
  • Molecular Conformation
  • Structure-Activity Relationship

Substances

  • Antineoplastic Agents
  • Macrolides
  • amphidinolide J
  • amphidinolide X