Intra-abdominal metastasis of an intracranial germinoma via ventriculo-peritoneal shunt in a 13-year-old female

Matthew J Murray; Lucy E Metayer; Conor L Mallucci; Juliet P Hale; James C Nicholson; Ramez W Kirollos; G A Amos Burke

doi:10.3109/02688697.2011.566383

Intra-abdominal metastasis of an intracranial germinoma via ventriculo-peritoneal shunt in a 13-year-old female

Br J Neurosurg. 2011 Dec;25(6):747-9. doi: 10.3109/02688697.2011.566383. Epub 2011 Apr 18.

Authors

Matthew J Murray¹, Lucy E Metayer, Conor L Mallucci, Juliet P Hale, James C Nicholson, Ramez W Kirollos, G A Amos Burke

Affiliation

¹ Department of Paediatric Haematology and Oncology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. [email protected]

PMID: 21501064
DOI: 10.3109/02688697.2011.566383

Abstract

A 13-year-old patient presented with massive intra-abdominal metastasis and spontaneous acute tumour lysis syndrome, 17-months after VP shunt placement for metastatic pineal germinoma treated with cranio-spinal-irradiation. Hyperhydration/rasburicase improved renal function, allowing chemotherapy with subsequent surgery. The patient remains event-free 34-months later. Risk of intra-abdominal metastasis from VP shunts is discussed.

Publication types

Case Reports

MeSH terms

Abdominal Neoplasms / diagnosis
Abdominal Neoplasms / drug therapy
Abdominal Neoplasms / secondary*
Adolescent
Antineoplastic Agents / administration & dosage
Ascites / etiology
Brain Neoplasms / diagnosis*
Brain Neoplasms / pathology
Brain Neoplasms / radiotherapy
Brain Neoplasms / surgery
Female
Germinoma / diagnosis*
Germinoma / radiotherapy
Germinoma / secondary
Germinoma / surgery
Humans
Magnetic Resonance Imaging
Neoplasm Seeding*
Pinealoma / diagnosis*
Pinealoma / radiotherapy
Pinealoma / secondary
Pinealoma / surgery
Tumor Lysis Syndrome / diagnosis
Tumor Lysis Syndrome / metabolism
Tumor Lysis Syndrome / therapy*
Ventriculoperitoneal Shunt / adverse effects

Substances

Antineoplastic Agents