Clean and modified substrates for direct detection of living cells by surface-enhanced Raman spectroscopy

Chem Commun (Camb). 2011 May 28;47(20):5738-40. doi: 10.1039/c0cc05323f. Epub 2011 Apr 18.

Abstract

Iodide adsorption and electrochemical negative potential desorption were proposed and compared to obtain clean SERS substrates. The two methods can effectively eliminate the interference of surface impurities in the SERS detection. SERS signals of membranes of living cells with a good reproducibility have been obtained.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Gold / chemistry
  • Iodides / chemistry
  • Metal Nanoparticles / chemistry
  • Propylamines / chemistry
  • Silanes / chemistry
  • Spectrum Analysis, Raman / methods*
  • Substrate Specificity
  • Surface Properties
  • Tin Compounds / chemistry

Substances

  • Iodides
  • Propylamines
  • Silanes
  • Tin Compounds
  • 3-aminopropyltrimethoxysilane
  • indium tin oxide
  • Gold