Abstract
In this article, we describe a chronic case of rhinofacial mucormycosis caused by Mucor irregularis, formerly known as Rhizomucor variabilis var. variabilis, a rare mycotic agent in humans. The infection caused progressive destruction of the nasal septum and soft and hard palate, leading to collapse of the nose bridge and an ulcerative gaping hole. The mucoralean mold cultured from a nasal biopsy specimen was determined by multilocus DNA sequence data to be conspecific with M. irregularis.
MeSH terms
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Adolescent
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Biopsy
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Cluster Analysis
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DNA, Fungal / chemistry
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DNA, Fungal / genetics
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DNA, Ribosomal / chemistry
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DNA, Ribosomal / genetics
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Fungal Proteins / genetics
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Genes, rRNA
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Humans
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India
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Male
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Molecular Sequence Data
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Mucormycosis / diagnosis*
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Mucormycosis / microbiology
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Mucormycosis / pathology
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Multilocus Sequence Typing
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Mycological Typing Techniques
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Nasal Septum / pathology
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Palate / pathology
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Peptide Elongation Factor 1 / genetics
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Phylogeny
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RNA, Fungal / genetics
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RNA, Ribosomal / genetics
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RNA, Ribosomal, 18S / genetics
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Rhizomucor / classification
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Rhizomucor / genetics
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Rhizomucor / isolation & purification*
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Sequence Analysis, DNA
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Skin Ulcer / pathology
Substances
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DNA, Fungal
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DNA, Ribosomal
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Fungal Proteins
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Peptide Elongation Factor 1
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RNA, Fungal
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RNA, Ribosomal
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RNA, Ribosomal, 18S
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RNA, ribosomal, 26S
Associated data
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GENBANK/HQ332515
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GENBANK/HQ332516
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GENBANK/HQ332517