Abstract
A highly stereoselective synthesis of a model C(18)-C(35) spiroketal unit (7) of integramycin has been accomplished via an enantioselective stannyl-crotylboration reaction and an N-iodosuccinimide-mediated spiroketalization of 19a.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Furans / chemistry*
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Models, Molecular*
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Molecular Structure
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Naphthalenes / chemistry*
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Spiro Compounds / chemical synthesis*
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Spiro Compounds / chemistry
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Stereoisomerism
Substances
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Furans
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Naphthalenes
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Spiro Compounds
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integramycin
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spiroketal