Overweight and obesity are the most common nutritional disorders in our age and are becoming more and more common worldwide. The most harmful consequences of an incorrect diet leading to overweight or obesity are a series of cardio-vascular diseases often leading to disability and death. In recent years various studies have shown that a reduction in caloric intake is the main factor involved in reduction of pathology risk. In this article, a nutrition strategy, based on the Zone diet by US biochemist Dr. Barry Sears is proposed. It underlines the importance of choosing certain types of foods over others, their beneficial physiological effects on the human body and how they can reduce the risk of heart disease and cancer.