Abstract
We report on the first detection of the NDM-1 carbapenemase in Italy, in Escherichia coli isolated in October 2009. Prolonged colonization and relapsing infection by NDM-1-positive E. coli were observed in a patient (index case) with an indirect epidemiological link with areas of endemicity. Transient colonization was apparently observed in another patient linked with the index case.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Carrier State / diagnosis*
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Carrier State / microbiology
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DNA, Bacterial / genetics
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Drug Resistance, Multiple, Bacterial*
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Electrophoresis, Gel, Pulsed-Field
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Escherichia coli / classification
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Escherichia coli / drug effects*
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Escherichia coli / enzymology*
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Escherichia coli / isolation & purification
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Escherichia coli Infections / diagnosis*
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Escherichia coli Infections / microbiology
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Genotype
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Humans
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Italy
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Microbial Sensitivity Tests
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Molecular Typing
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Recurrence
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beta-Lactamases / biosynthesis*
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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beta-Lactamases
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beta-lactamase NDM-1