[Patients with an indeterminate serological diagnosis of HIV-1 infection]

Rev Med Chil. 1990 Nov;118(11):1235-40.
[Article in Spanish]

Abstract

Western blot is the technique most frequently used to determine the presence of HIV-1 antibodies. However, some patients remain with an indeterminate diagnosis for HIV-1 according to the technique. We followed 8 such patients for 2 to 18 months. Immunologic studies included standard ELISA, immunofluorescence and Abbott anti-p24 ELISA. We found selective reactivity for certain viral proteins such as isolated p24, p24 plus p51 or p55, gp41 plus gp 120, p17 plus p24 and p25.

MeSH terms

  • AIDS Serodiagnosis* / methods
  • AIDS Serodiagnosis* / statistics & numerical data
  • Algorithms
  • Blotting, Western
  • Chile / epidemiology
  • Chromobox Protein Homolog 5
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Fluorescent Antibody Technique
  • Follow-Up Studies
  • HIV Antibodies / blood
  • HIV Antigens / blood
  • HIV Infections / diagnosis*
  • HIV Infections / epidemiology
  • HIV-1* / immunology
  • Humans
  • Male
  • Time Factors

Substances

  • CBX5 protein, human
  • HIV Antibodies
  • HIV Antigens
  • Chromobox Protein Homolog 5