Abstract
We conducted a complete genome analysis of a West Nile virus detected in Culex pipiens mosquitoes during a severe outbreak of human West Nile disease in Greece 2010. The virus showed closest genetic relationship to the lineage 2 strain that emerged in Hungary in 2004; increased virulence may be associated with amino acid substitution H249P.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Substitution / genetics
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Animals
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Culex / virology
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Genetic Linkage / genetics
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Greece
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Humans
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Molecular Sequence Data
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Phylogeny
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RNA, Viral / genetics
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Viral Nonstructural Proteins / genetics
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West Nile Fever / virology*
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West Nile virus / classification
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West Nile virus / genetics*
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West Nile virus / isolation & purification
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West Nile virus / pathogenicity
Substances
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RNA, Viral
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Viral Nonstructural Proteins