[Interpretation of the susceptibility test results in enterobacteria producing 3rd- and 4th-generation cephalosporin- or carbapenem-hydrolyzing beta-lactamases]

J Hrabák; H Zemlicková; T Bergerová; P Urbásková

[Interpretation of the susceptibility test results in enterobacteria producing 3rd- and 4th-generation cephalosporin- or carbapenem-hydrolyzing beta-lactamases]

Epidemiol Mikrobiol Imunol. 2011 Feb;60(1):4-9.

[Article in Czech]

Authors

J Hrabák¹, H Zemlicková, T Bergerová, P Urbásková

Affiliation

¹ Ustav mikrobiologie, Lékarská fakulta UK a Fakultní nemocnice v Plzni. [email protected]

PMID: 21542230

Abstract

The interpretation of the susceptibility of Gram-negative rods to beta-lactams is currently under discussion in CLSI and EUCAST--two authorities on determination of clinical breakpoints. This article summarizes the current knowledge about clinical breakpoints in enterobacteria and proposes guidance for clinical microbiology laboratories in the Czech Republic.

Publication types

English Abstract

MeSH terms

Carbapenems / pharmacokinetics
Carbapenems / pharmacology*
Cephalosporins / pharmacokinetics
Cephalosporins / pharmacology*
Enterobacteriaceae / drug effects*
Enterobacteriaceae / enzymology*
Enterobacteriaceae / metabolism
Hydrolysis
Microbial Sensitivity Tests
beta-Lactamases / biosynthesis*
beta-Lactams / pharmacokinetics
beta-Lactams / pharmacology*

Substances

Carbapenems
Cephalosporins
beta-Lactams
beta-Lactamases