The affinity ligand "UPHIT" acylates kappa opioid binding sites in vivo

Prog Clin Biol Res. 1990:328:77-80.
No abstract available

MeSH terms

  • Acylation
  • Animals
  • Benzeneacetamides*
  • Binding Sites
  • Brain / metabolism
  • Cyclohexanes / metabolism*
  • Guinea Pigs
  • Male
  • Pyrrolidines / metabolism*
  • Receptors, Opioid / drug effects
  • Receptors, Opioid / metabolism*
  • Receptors, Opioid, delta
  • Receptors, Opioid, kappa
  • Receptors, Opioid, mu

Substances

  • Benzeneacetamides
  • Cyclohexanes
  • Pyrrolidines
  • Receptors, Opioid
  • Receptors, Opioid, delta
  • Receptors, Opioid, kappa
  • Receptors, Opioid, mu
  • 2-isothiocyanato-4,5-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)benzeneacetamide