KRAS-mutation positive, metastatic tonsil carcinoma with cancer stem-like cell features and long-term response to gefitinib: a case report and review of the literature

MeSH terms

• Antineoplastic Agents / therapeutic use*
• Biopsy
• Carcinoma, Squamous Cell / diagnostic imaging
• Carcinoma, Squamous Cell / drug therapy*
• Carcinoma, Squamous Cell / genetics
• Carcinoma, Squamous Cell / secondary
• ErbB Receptors / antagonists & inhibitors
• ErbB Receptors / genetics
• Fatal Outcome
• Female
• Gefitinib
• Humans
• Immunohistochemistry
• In Situ Hybridization, Fluorescence
• Lung Neoplasms / diagnostic imaging
• Lung Neoplasms / drug therapy*
• Lung Neoplasms / genetics
• Lung Neoplasms / secondary
• Lymphatic Metastasis
• Middle Aged
• Mutation*
• Neoplasm Invasiveness
• Neoplasm Staging
• Protein Kinase Inhibitors / therapeutic use*
• Proto-Oncogene Proteins / genetics*
• Proto-Oncogene Proteins p21(ras)
• Quinazolines / therapeutic use*
• Time Factors
• Tomography, X-Ray Computed
• Tonsillar Neoplasms / diagnostic imaging
• Tonsillar Neoplasms / drug therapy*
• Tonsillar Neoplasms / genetics
• Tonsillar Neoplasms / pathology
• Treatment Outcome
• ras Proteins / genetics*