A gene for cytochrome c oxidase subunit III (COXIII) in broad bean mitochondrial DNA: structural features and sequence evolution

Curr Genet. 1990 Jan;17(1):33-40. doi: 10.1007/BF00313246.

Abstract

A nucleotide sequence of broad bean mitochondrial DNA (mtDNA) that contains the coxIII gene is presented, and compared to corresponding sequences of Oenothera and corn mtDNAs. Upstream from the broad bean coxIII gene are three potential secondary structures: a single stem and loop (hairpin) that is conserved in the Oenothera and corn sequences; a second single stem and loop; and a double stem and loop. The rate of evolution of the coxIII gene has been slower in plants than in mammals. Constraints on the fixation of at least some kinds of mutations in silent (synonymous) third position nucleotides, as well as of mutations that cause amino acid replacements, seem to have contributed to this slower rate.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Biological Evolution
  • Codon
  • DNA, Mitochondrial / genetics*
  • Electron Transport Complex IV / genetics*
  • Fabaceae / enzymology
  • Fabaceae / genetics*
  • Genes, Plant*
  • Molecular Sequence Data
  • Mutation
  • Nucleic Acid Conformation
  • Plants, Medicinal*
  • Sequence Homology, Nucleic Acid
  • Zea mays / genetics

Substances

  • Codon
  • DNA, Mitochondrial
  • Electron Transport Complex IV