Immune therapy for ovarian cancer: promise and pitfalls

Int Rev Immunol. 2011 Apr-Jun;30(2-3):102-19. doi: 10.3109/08830185.2011.567361.

Abstract

This review covers immune and anatomic considerations specific for ovarian cancer immune therapy. Prior approaches and potential reasons for lack of better efficacy are discussed, along with newer approaches in pre-clinical and early clinical development. Potential means for future investigations and means to integrate immune with other approaches are discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Antibodies / immunology
  • Antibodies / therapeutic use
  • Antigens, Neoplasm / immunology
  • Antigens, Neoplasm / therapeutic use
  • Cancer Vaccines / immunology
  • Cancer Vaccines / therapeutic use
  • Clinical Trials as Topic
  • Cytokines / immunology
  • Cytokines / therapeutic use
  • Female
  • Humans
  • Immunotherapy / methods*
  • Ovarian Neoplasms / immunology*
  • Ovarian Neoplasms / therapy*
  • Treatment Outcome

Substances

  • Antibodies
  • Antigens, Neoplasm
  • Cancer Vaccines
  • Cytokines