Abstract
We report a case of a 64 year old woman with spontaneous hematomas. A prior history of bleeding disorder was not known up to now. The result of investigation of coagulation was an isolated prolonged aPTT that was caused by an inhibitor of factor VIII without underlying disease (idiopathic acquired hemophilia A). Therapy with steroids and cyclophosphamid resulted in partial remission.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Algorithms
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Cyclophosphamide / therapeutic use
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Diagnosis, Differential
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Drug Therapy, Combination
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Factor VIII / antagonists & inhibitors*
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Female
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Hematoma / blood*
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Hematoma / drug therapy
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Hematoma / etiology*
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Hemophilia A / blood
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Hemophilia A / diagnosis
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Hemophilia A / drug therapy
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Hemorrhagic Disorders / blood*
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Hemorrhagic Disorders / drug therapy
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Hemorrhagic Disorders / etiology*
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Humans
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Immunosuppressive Agents / therapeutic use
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Methylprednisolone / therapeutic use
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Middle Aged
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Partial Thromboplastin Time*
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Prednisolone / therapeutic use
Substances
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Immunosuppressive Agents
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Cyclophosphamide
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Factor VIII
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Prednisolone
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Methylprednisolone
Supplementary concepts
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Factor 8 deficiency, acquired