Familial or genetic primary aldosteronism and Gordon syndrome

Endocrinol Metab Clin North Am. 2011 Jun;40(2):343-68, viii. doi: 10.1016/j.ecl.2011.01.007.

Abstract

Salt-sensitive forms of hypertension have received considerable renewed attention in recent years. This article focuses on 2 main forms of salt-sensitive hypertension (familial or genetic primary aldosteronism [PA] and Gordon syndrome) and the current state of knowledge regarding their genetic bases. The glucocorticoid-remediable form of familial PA (familial hyperaldosteronism type I) is dealt with only briefly because it is covered in depth elsewhere.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arthrogryposis / diagnosis
  • Arthrogryposis / genetics
  • Arthrogryposis / physiopathology
  • Arthrogryposis / therapy
  • Cleft Palate / diagnosis
  • Cleft Palate / genetics
  • Cleft Palate / physiopathology
  • Cleft Palate / therapy
  • Clubfoot / diagnosis
  • Clubfoot / genetics
  • Clubfoot / physiopathology
  • Clubfoot / therapy
  • Diagnosis, Differential
  • Disease Models, Animal
  • Genetic Variation
  • Hand Deformities, Congenital / diagnosis
  • Hand Deformities, Congenital / genetics
  • Hand Deformities, Congenital / physiopathology
  • Hand Deformities, Congenital / therapy
  • Humans
  • Hyperaldosteronism / diagnosis
  • Hyperaldosteronism / genetics*
  • Hyperaldosteronism / physiopathology*
  • Hyperaldosteronism / therapy
  • Lithium / pharmacokinetics
  • Metabolic Clearance Rate
  • Sodium Chloride, Dietary / adverse effects

Substances

  • Sodium Chloride, Dietary
  • Lithium

Supplementary concepts

  • Gordon syndrome