The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical

G R Buettner; W Chamulitrat

doi:10.1016/0891-5849(90)90144-8

The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical

Free Radic Biol Med. 1990;8(1):55-6. doi: 10.1016/0891-5849(90)90144-8.

Authors

G R Buettner¹, W Chamulitrat

Affiliation

¹ ESR Center, College of Medicine, University of Iowa, Iowa City 52242.

PMID: 2157634
DOI: 10.1016/0891-5849(90)90144-8

Abstract

Human synovial fluid, from a patient with synovitis disease, was examined by electron spin resonance spectroscopy for evidence of free radicals. The ascorbate free radical was observed and its intensity was affected by iron chelating agents, demonstrating that the iron in the synovial fluid is indeed available for oxidative catalysis.

MeSH terms

Ascorbic Acid / analysis*
Deferoxamine / pharmacology
Electron Spin Resonance Spectroscopy
Free Radicals
Humans
Iron / metabolism*
Oxidation-Reduction
Pentetic Acid / pharmacology
Synovial Fluid / analysis*
Synovitis, Pigmented Villonodular / metabolism

Substances

Free Radicals
Pentetic Acid
Iron
Deferoxamine
Ascorbic Acid