Disappearance of IgM antibodies to hepatitis A virus after an acute infection in children and adolescents

J Pediatr Gastroenterol Nutr. 1990 Apr;10(3):307-9. doi: 10.1097/00005176-199004000-00007.

Abstract

The kinetics of IgM antibodies to hepatitis A virus (HAV) following an acute infection, were studied in 17 children. Antibodies disappeared in two patterns, one group at 113 +/- 18 days after the acute infection in the children, and the second group at 283 +/- 90 days. The same two patterns of kinetics were seen in adults. We conclude that IgM anti-HAV antibodies can be found in the sera of children for over 6 months after the acute infection, as was observed in adults.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adolescent
  • Age Factors
  • Child
  • Child, Preschool
  • Hepatitis Antibodies / analysis*
  • Hepatitis, Viral, Human / immunology*
  • Hepatitis, Viral, Human / microbiology
  • Hepatovirus / immunology*
  • Humans
  • Immunoglobulin M / analysis*
  • Prospective Studies
  • Time Factors

Substances

  • Hepatitis Antibodies
  • Immunoglobulin M