In the title compound, C(27)H(32)N(2)O(5), the morpholine ring adopts a chair conformation with two C atoms deviating by -0.656 (4) and 0.679 (3) Å from the least-squares plane defined by the rest of atoms in the ring. The tetra-hydro-pyridine ring adopts a half-chair conformation. The mol-ecular structure is stabilized by a strong intra-molecular O-H⋯O inter-action, generating an S(6) motif. The crystal packing is stabilized by inter-molecular C-H⋯O inter-actions, generating a C(7) chain along the a axis, and R(2) (2)(20) and R(4) (4)(20) graph-set motifs.