Management of lung cancer-associated anaemia: the Spanish Lung Cancer Anaemia Survey (SLCAS)

Clin Transl Oncol. 2011 May;13(5):328-34. doi: 10.1007/s12094-011-0662-5.

Abstract

Background: The purpose of the Spanish Lung Cancer Anaemia Survey (SLCAS) was to thoroughly investigate lung cancer-associated anaemia management, and describe the profile of lung cancer patients in relation to anaemia incidence and tumour type in Spain.

Patients and methods: This survey collected data from 1089 randomly recruited patients gathered by 50 Spanish physicians at 38 sites. In addition, a qualitative assay was performed through 16 one-to-one and 2 one-to-two interviews, and a discussion group of 4 cancer specialists participating in the survey.

Results: Lung cancer patients undergoing chemotherapy treatment had haemoglobin (Hb) levels <12.0 g/dl in 58.0% of the cases, in contrast to 39.0% of patients receiving no chemotherapy. Anaemia was treated in 53.0% of patients with Hb<12 g/dl (45.0% epoetin, 3.9% transfusion, 4.1% iron). Mean Hb level trigger was 9.7 g/dl for administration of epoetin and 8.2 g/dl for blood transfusion.

Conclusions: SLCAS reveals a significant change in the management of anaemia and clinical practice pattern in the use of erythropoiesis-stimulating agents (45.0% vs. 18.0%) and much less use of blood transfusions (3.9% vs. 15.0%) since the European Cancer Anaemia Survey performed five years ago.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anemia / complications
  • Anemia / etiology*
  • Anemia / therapy*
  • Antineoplastic Agents / adverse effects
  • Blood Transfusion
  • Female
  • Hematinics / therapeutic use
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / therapy*
  • Male
  • Medical Oncology / methods
  • Middle Aged
  • Quality of Life
  • Spain
  • Surveys and Questionnaires

Substances

  • Antineoplastic Agents
  • Hematinics