Enzyme-magnetic nanoparticle conjugates as a rigid biocatalyst for the elimination of toxic aromatic hydrocarbons

Chem Commun (Camb). 2011 Sep 28;47(36):9989-91. doi: 10.1039/c1cc11664a. Epub 2011 May 23.

Abstract

An enzyme-magnetic nanoparticle conjugate is prepared via conjugation of Ni(2+) ions onto the surface of magnetic nanoparticles to interact with a six histidine-tagged enzyme. The catalytic properties and enzyme rigidification of the conjugates are more stable at high concentrations of aromatic hydrocarbons.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis
  • Catechol 1,2-Dioxygenase / chemistry
  • Catechol 1,2-Dioxygenase / genetics
  • Catechol 1,2-Dioxygenase / metabolism
  • Enzymes / chemistry
  • Enzymes / genetics
  • Enzymes / metabolism*
  • Ferrosoferric Oxide / chemistry
  • Histidine / genetics
  • Histidine / metabolism
  • Hydrocarbons, Aromatic / chemistry
  • Hydrocarbons, Aromatic / metabolism*
  • Magnetite Nanoparticles / chemistry*
  • Nickel / chemistry
  • Oligopeptides / genetics
  • Oligopeptides / metabolism

Substances

  • Enzymes
  • His-His-His-His-His-His
  • Hydrocarbons, Aromatic
  • Magnetite Nanoparticles
  • Oligopeptides
  • Histidine
  • Nickel
  • Catechol 1,2-Dioxygenase
  • Ferrosoferric Oxide