Marked QT prolongation and ventricular tachycardia of a transient nature in young children with cardiomyopathy

Pacing Clin Electrophysiol. 2012 Aug;35(8):e247-50. doi: 10.1111/j.1540-8159.2011.03126.x. Epub 2011 May 23.

Abstract

Significant prolongation of the QT interval in pediatric patients with cardiomyopathy is rare. We report two cases of dilated myopathy with transient and dramatic QT prolongation. Both had associated ventricular arrhythmias, with one having torsade de pointes, and the other nonsustained ventricular tachycardia. Normalization of their QTc occurred as their ventricular function improved.

Publication types

  • Case Reports

MeSH terms

  • Carbazoles / therapeutic use
  • Cardiomyopathies / diagnosis*
  • Cardiomyopathies / drug therapy
  • Cardiotonic Agents / therapeutic use
  • Carvedilol
  • Child
  • Electrocardiography
  • Humans
  • Infant
  • Long QT Syndrome / diagnosis*
  • Long QT Syndrome / drug therapy
  • Male
  • Propanolamines / therapeutic use
  • Tachycardia, Ventricular / diagnosis*
  • Tachycardia, Ventricular / drug therapy
  • Treatment Outcome

Substances

  • Carbazoles
  • Cardiotonic Agents
  • Propanolamines
  • Carvedilol