Evidence of circulation of an epidemic strain of Francisella tularensis in France by multispacer typing

W Li; D Raoult; J-M Rolain; B La Scola

doi:10.1007/s10096-011-1186-1

Evidence of circulation of an epidemic strain of Francisella tularensis in France by multispacer typing

Eur J Clin Microbiol Infect Dis. 2011 Sep;30(9):1135-8. doi: 10.1007/s10096-011-1186-1. Epub 2011 May 25.

Authors

W Li¹, D Raoult, J-M Rolain, B La Scola

Affiliation

¹ Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes, CNRS-IRD UMR 6236, Faculté de Médecine, Université de la Méditerranée, 27 Boulevard Jean Moulin, 13385 Marseille cedex 05, France.

PMID: 21611870
DOI: 10.1007/s10096-011-1186-1

Abstract

Multispacer typing (MST) was used to type ten Francisella tularensis strains detected in French patients. Incorporating 79 Swedish F. tularensis strains, phylogenetic analysis demonstrated that although tularemia appears as a sporadic disease in France, it is caused by an epidemic cluster of strains.

MeSH terms

Cluster Analysis
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
France / epidemiology
Francisella tularensis / classification*
Francisella tularensis / genetics
Francisella tularensis / isolation & purification*
Humans
Molecular Sequence Data
Molecular Typing*
Phylogeny
Sequence Analysis, DNA
Tularemia / epidemiology*
Tularemia / microbiology*

Substances

DNA, Bacterial

Associated data

GENBANK/EU877932
GENBANK/EU877933
GENBANK/EU877934
GENBANK/EU877935