The nature and structure of psychological distress in people at high risk for melanoma: a factor analytic study

Psychooncology. 2012 Aug;21(8):845-56. doi: 10.1002/pon.1976. Epub 2011 May 24.

Abstract

Objective: This study examined the psychometric properties of two commonly used measures of psychological distress, the Hospital Anxiety and Depression Scale (HADS) and the Impact of Events Scale (IES) in a sample of individuals at high risk of developing melanoma due to strong family history.

Methods: One hundred thirty-two individuals with a known family-specific CDKN2A mutation (74% response rate) completed a mailed, self-administered questionnaire including the HADS and the IES. Initial correlational analyses were followed by both exploratory and confirmatory factor analyses, according to a predetermined procedure for order of analyses.

Results: Exploratory factor analyses found that neither a two-, three- or four-factor solution satisfactorily accounted for all IES items in the present sample. By contrast, a unidimensional account of the data emerged to best account for all IES items, leaving no items unaccounted for. In contrast, the traditional two-factor (anxiety and depression) structure of the HADS appeared to fit the data well.

Conclusions: The traditional, two-factor (intrusion and avoidance) structure of the IES was not borne out within this familial melanoma cohort. Assessment of a single dimension of emotional distress in response to melanoma risk may facilitate more meaningful explorations of psychological adjustment in this context. These findings also raise questions about whether a post-traumatic stress framework is indeed the most appropriate framework to capture the unique nature of melanoma- or cancer-related distress.

Keywords: anxiety; cancer; depression; factor analysis; melanoma; oncology; psychological distress.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anxiety / psychology*
  • Depression / psychology*
  • Factor Analysis, Statistical
  • Female
  • Genes, p16
  • Genetic Predisposition to Disease / psychology*
  • Humans
  • Male
  • Melanoma / genetics
  • Melanoma / psychology*
  • Melanoma, Cutaneous Malignant
  • Middle Aged
  • Psychometrics
  • Skin Neoplasms
  • Stress, Psychological / psychology*
  • Surveys and Questionnaires
  • Young Adult