A strategy for producing predicted polymorphs: catemeric carbamazepine form V

Jean-Baptiste Arlin; Louise S Price; Sarah L Price; Alastair J Florence

doi:10.1039/c1cc11634g

A strategy for producing predicted polymorphs: catemeric carbamazepine form V

Chem Commun (Camb). 2011 Jul 7;47(25):7074-6. doi: 10.1039/c1cc11634g. Epub 2011 May 26.

Authors

Jean-Baptiste Arlin¹, Louise S Price, Sarah L Price, Alastair J Florence

Affiliation

¹ Solid-State Research Group, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow, G4 0NR, UK.

PMID: 21614395
DOI: 10.1039/c1cc11634g

Abstract

A computationally assisted approach has enabled the first catemeric polymorph of carbamazepine (form V) to be selectively formed by templating the growth of carbamazepine from the vapour phase onto the surface of a crystal of dihydrocarbamazepine form II.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anticonvulsants / chemistry*
Carbamazepine / chemistry*
Crystallography, X-Ray
Models, Molecular
Molecular Conformation
Thermodynamics

Substances

Anticonvulsants
Carbamazepine