Suprachoroidal implant surgery in intractable glaucoma

Jpn J Ophthalmol. 2011 Jul;55(4):351-355. doi: 10.1007/s10384-011-0035-1. Epub 2011 May 27.

Abstract

Purpose: To report the early results of suprachoroidal silicone implant surgery in intractable glaucoma.

Materials and methods: A modified silicone implant with no valve was implanted into the suprachoroidal space of 15 eyes with intractable glaucoma.

Results: The mean age of the patients was 53.0 ± 24.5 (range 7-85) years, the mean follow-up time was 17.1 ± 4.8 (range 10-28) months, and the mean preoperative intraocular pressure (IOP) of patients receiving two or more medications was 33.1 ± 9.8 mmHg. At the last follow-up visit, mean IOP was 16.5 ± 7.9 (range 10-35) mmHg (Wilcoxon signed rank test, p = 0.001). The functional success, i.e., IOP ≤21 mmHg both with and without antiglaucomatous drugs, was 93.3%. The total success rate, i.e., IOP ≤21 mmHg without medication, was 13.3%. The average number of antiglaucomatous drugs used was 3.8 (range 2-5) preoperatively, and 2.2 postoperatively (range 0-4) (Wilcoxon signed rank test, p = 0.011). There was a ≥30% decrease in the IOP of 66.6% of the eyes. Shallow choroidal detachment as proof of drainage was evident in all cases.

Conclusion: Drainage of the aqueous humor from the anterior chamber to the suprachoroidal space via implantation of a modified silicone implant is effective in lowering the IOP in intractable glaucoma.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use
  • Aqueous Humor / metabolism
  • Child
  • Choroid / surgery*
  • Female
  • Follow-Up Studies
  • Glaucoma Drainage Implants*
  • Glaucoma, Open-Angle / physiopathology
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Silicones*
  • Surgical Flaps
  • Tonometry, Ocular
  • Young Adult

Substances

  • Antihypertensive Agents
  • Silicones