Abstract
Anaplastic large cell lymphoma (ALCL) is a distinct subset of T-cell non-Hodgkin's lymphoma. As a consequence of its low incidence, general pathogenic consideration of ALCL is lacking. In this review, we summarize the pathogenesis, epidemiology, clinical manifestations, and treatment of ALCL, so as to better understand key stages of the development of this disease and provide valuable information for future treatment.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Anaplastic Lymphoma Kinase
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Combined Modality Therapy
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Humans
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Ki-1 Antigen / metabolism*
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Lymphoma, Large-Cell, Anaplastic / epidemiology
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Lymphoma, Large-Cell, Anaplastic / etiology*
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Lymphoma, Large-Cell, Anaplastic / metabolism
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Lymphoma, Large-Cell, Anaplastic / therapy
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Radiotherapy
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Receptor Protein-Tyrosine Kinases / metabolism*
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Stem Cell Transplantation
Substances
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Ki-1 Antigen
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Anaplastic Lymphoma Kinase
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Receptor Protein-Tyrosine Kinases