[Infectious complications of the treatment of acute lymphoblastic leukemia in children]

H Rubie; C Assouline; M F Prere; A Dutour; J Lemozy; J L Mouls; C Gayet-Mengelle; A Robert

[Infectious complications of the treatment of acute lymphoblastic leukemia in children]

Pediatrie. 1990;45(5):333-8.

[Article in French]

Authors

H Rubie¹, C Assouline, M F Prere, A Dutour, J Lemozy, J L Mouls, C Gayet-Mengelle, A Robert

Affiliation

¹ Médecine infantile B, CHU Purpan, Toulouse, France.

PMID: 2165247

Abstract

The authors report the infectious complications observed during the treatment of acute lymphoblastic leukemia in 70 children, followed by a same team, with the same protocole, for a period of 6 years (mean follow-up: 42.3 months). The complications were mainly bacterial during induction phase, mainly staphylococcic the microbiological follow-up and a rapid empiric antibiotic therapy allowed to control more than 80% of the febrile episodes. There was one death from fulminant pyocyanic infection.

Publication types

English Abstract

MeSH terms

Adolescent
Anti-Bacterial Agents
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bacterial Infections / drug therapy
Bacterial Infections / etiology*
Child
Child, Preschool
Drug Therapy, Combination / therapeutic use
Female
Follow-Up Studies
Humans
Iatrogenic Disease
Infant
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Retrospective Studies
Risk Factors
Virus Diseases / etiology

Substances

Anti-Bacterial Agents