Early detection of colonization by VIM-1-producing Klebsiella pneumoniae and NDM-1-producing Escherichia coli in two children returning to France

André Birgy; Catherine Doit; Patricia Mariani-Kurkdjian; Nathalie Genel; Albert Faye; Guillaume Arlet; Edouard Bingen

doi:10.1128/JCM.00540-11

Early detection of colonization by VIM-1-producing Klebsiella pneumoniae and NDM-1-producing Escherichia coli in two children returning to France

J Clin Microbiol. 2011 Aug;49(8):3085-7. doi: 10.1128/JCM.00540-11. Epub 2011 Jun 8.

Authors

André Birgy¹, Catherine Doit, Patricia Mariani-Kurkdjian, Nathalie Genel, Albert Faye, Guillaume Arlet, Edouard Bingen

Affiliation

¹ Hôpital Robert Debré (APHP), Service de microbiologie, 48 boulevard Sérurier, 75935 Paris CEDEX 19, France.

Abstract

Rapid identification of metallo-β-lactamase-producing Gram-negative species is crucial for the timely implementation of infection control measures. We describe two pediatric cases in which colonization by VIM-1- and New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae was rapidly detected by phenotypic and genotypic methods. Phenotypic methods can be useful for routine detection of carbapenemase production.

Publication types

Case Reports

MeSH terms

Bacteriological Techniques / methods
Escherichia coli / enzymology*
Escherichia coli / isolation & purification
Escherichia coli Infections / diagnosis*
Escherichia coli Infections / microbiology
France
Genotype
Humans
Infant
Klebsiella Infections / diagnosis*
Klebsiella Infections / microbiology
Klebsiella pneumoniae / enzymology*
Klebsiella pneumoniae / isolation & purification
Male
Phenotype
beta-Lactamases / biosynthesis*

Substances

VIM-1 metallo-beta-lactamase
beta-Lactamases
beta-lactamase NDM-1