Clostridium difficile in children: colonisation and disease

David A Enoch; Matthew J Butler; Sumita Pai; Sani H Aliyu; J Andreas Karas

doi:10.1016/j.jinf.2011.05.016

Clostridium difficile in children: colonisation and disease

J Infect. 2011 Aug;63(2):105-13. doi: 10.1016/j.jinf.2011.05.016. Epub 2011 Jun 12.

Authors

David A Enoch¹, Matthew J Butler, Sumita Pai, Sani H Aliyu, J Andreas Karas

Affiliation

¹ Clinical Microbiology and Public Health Laboratory, Peterborough and Stamford NHS Foundation Trust, Peterborough City Hospital, Bretton Gate, Peterborough, PE3 9GZ, UK.

PMID: 21664931
DOI: 10.1016/j.jinf.2011.05.016

Abstract

Clostridium difficile is the commonest cause of hospital acquired diarrhoea in adults and is associated with significant mortality and morbidity. The clinical significance of C. difficile in children, however, is less certain. In this article we discuss colonisation and infection and describe C. difficile in childhood in terms of risk factors, epidemiology and management.

Publication types

Review

MeSH terms

Adolescent
Carrier State / drug therapy
Carrier State / epidemiology*
Carrier State / microbiology*
Carrier State / prevention & control
Child
Child, Preschool
Clostridioides difficile / isolation & purification*
Clostridium Infections / drug therapy
Clostridium Infections / epidemiology*
Clostridium Infections / microbiology*
Clostridium Infections / prevention & control
Cross Infection / drug therapy
Cross Infection / epidemiology
Cross Infection / microbiology
Cross Infection / prevention & control
Diarrhea / drug therapy
Diarrhea / epidemiology
Diarrhea / microbiology
Diarrhea / prevention & control
Humans
Infant
Infant, Newborn
Risk Factors