Abstract
Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.
© 2011 John Wiley & Sons A/S.
MeSH terms
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Acinetobacter / immunology
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Acinetobacter Infections / immunology
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Animals
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Environment*
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Epigenesis, Genetic
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Female
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Gene Expression Regulation
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Humans
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Hypersensitivity / genetics*
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Hypersensitivity / immunology*
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Hypersensitivity / prevention & control
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Interferon-gamma / biosynthesis
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Interferon-gamma / genetics
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Interferon-gamma / immunology
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Maternal-Fetal Exchange / immunology
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Pregnancy
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T-Lymphocytes / immunology