p16 immunohistochemistry of multiple primary melanomas as screening to identify Familial Melanoma Syndrome

Int J Dermatol. 2012 Apr;51(4):488-92. doi: 10.1111/j.1365-4632.2010.04496.x. Epub 2011 Jun 15.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adaptor Proteins, Signal Transducing / metabolism
  • Adult
  • Aged
  • Aged, 80 and over
  • Base Sequence*
  • Cadherins / metabolism
  • Cyclin-Dependent Kinase Inhibitor p16 / genetics
  • Cyclin-Dependent Kinase Inhibitor p16 / metabolism*
  • Female
  • Genetic Testing
  • Humans
  • Immunohistochemistry
  • Male
  • Melanoma / genetics
  • Melanoma / metabolism*
  • Middle Aged
  • MutL Protein Homolog 1
  • MutS Homolog 2 Protein / metabolism
  • Mutation, Missense
  • Neoplasms, Multiple Primary / genetics
  • Neoplasms, Multiple Primary / metabolism*
  • Nuclear Proteins / metabolism
  • Pedigree
  • Sequence Deletion*
  • Skin Neoplasms / genetics
  • Skin Neoplasms / metabolism*
  • Syndrome
  • Tumor Suppressor Protein p53 / metabolism
  • Young Adult
  • beta Catenin / metabolism

Substances

  • Adaptor Proteins, Signal Transducing
  • Cadherins
  • Cyclin-Dependent Kinase Inhibitor p16
  • MLH1 protein, human
  • Nuclear Proteins
  • Tumor Suppressor Protein p53
  • beta Catenin
  • MSH2 protein, human
  • MutL Protein Homolog 1
  • MutS Homolog 2 Protein