Modulation of rat Kupffer cells on high density lipoprotein receptors on hepatocytes

Sci China B. 1990 May;33(5):584-91.

Abstract

The present study found that conditioned media from Kupffer cells preincubated with acetylated LDL or acetylated LDL and zymosan increased the number of HDL receptors on hepatocytes, using the method of conditioned media transfer. This indicated that the transferable factors produced by Kupffer cells modulate HDL receptors on hepatocytes.

MeSH terms

  • Animals
  • Carrier Proteins*
  • Cells, Cultured
  • Culture Media
  • Kupffer Cells / physiology*
  • Lipoproteins, HDL
  • Lipoproteins, LDL / pharmacology
  • Liver / cytology*
  • Male
  • RNA-Binding Proteins*
  • Rats
  • Rats, Inbred Strains
  • Receptors, Cell Surface / metabolism*
  • Receptors, Lipoprotein*
  • Zymosan / pharmacology

Substances

  • Carrier Proteins
  • Culture Media
  • Lipoproteins, HDL
  • Lipoproteins, LDL
  • RNA-Binding Proteins
  • Receptors, Cell Surface
  • Receptors, Lipoprotein
  • high density lipoprotein receptors
  • high density lipoprotein binding protein
  • Zymosan