Efflux pumps of gram-negative bacteria: genetic responses to stress and the modulation of their activity by pH, inhibitors, and phenothiazines

Adv Enzymol Relat Areas Mol Biol. 2011:77:61-108. doi: 10.1002/9780470920541.ch2.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • DNA, Superhelical / genetics
  • Drug Resistance, Bacterial / genetics
  • Drug Resistance, Multiple / genetics
  • Escherichia coli Proteins / genetics
  • Genes, Bacterial
  • Gram-Negative Bacteria / genetics*
  • Humans
  • Hydrogen-Ion Concentration
  • Models, Biological
  • Models, Genetic
  • Multidrug Resistance-Associated Proteins / genetics
  • Mutation
  • Phenothiazines / chemistry*
  • Quinolones / pharmacology
  • Salmonella / genetics
  • Salmonella / metabolism
  • Time Factors

Substances

  • AcrB protein, E coli
  • Anti-Bacterial Agents
  • DNA, Superhelical
  • Escherichia coli Proteins
  • Multidrug Resistance-Associated Proteins
  • Phenothiazines
  • Quinolones