[Left-sided ulcerative colitis reactivated and aggravated during clostridium difficile infection]

Korean J Gastroenterol. 2011 Jun;57(6):374-8. doi: 10.4166/kjg.2011.57.6.374.
[Article in Korean]

Abstract

Clostridium difficile (C. difficile) infection appears to be closely related to reactivation, diagnostic delay, and disease progression in patients with inflammatory bowel disease. However, whether C. difficile infection triggers the reactivation of inflammatory bowel disease or vice versa is not certain. We report a case of reactivated and progressed left ulcerative colitis following C. difficile infection in a 56-year-old woman. A series of endoscopic findings in this case report strongly supports a causative role of C. difficile infection on the reactivation and progression of ulcerative colitis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • C-Reactive Protein / analysis
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / complications
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / drug therapy
  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / etiology
  • Colitis, Ulcerative / pathology
  • Colonoscopy
  • Drug Therapy, Combination
  • Feces / microbiology
  • Female
  • Humans
  • Metronidazole / therapeutic use
  • Middle Aged
  • Sulfasalazine / therapeutic use
  • Vancomycin / therapeutic use

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Metronidazole
  • Sulfasalazine
  • Vancomycin
  • C-Reactive Protein