[Unusual presentation of mycetoma caused by Actinomadurella pelletieri on the scalp]

Med Trop (Mars). 2011 Apr;71(2):179-80.
[Article in French]

Abstract

Introduction: Mycetoma is chronic inflammatory process characterized by areas of tumefaction with draining sinus tracts. It affects the foot in 80% of cases. The purpose of this report is to describe a case that posed a diagnostic challenge due to unusual scalp location and clinical presentation.

Observation: A 23-year-old woman residing in a rural zone of Senegal consulted for indolent lesions ongoing on the scalp for 2 years. Physical examination showed two soft tumid lesions measuring about 3 cm in diameter on the vertex. The surface of the lesions was crusty but showed no sign of granules. Skull x-ray was normal. Skin biopsy demonstrated a polymorphous granulomatous infiltrate with foci of suppuration circumscribing small, irregular grains with radiating filaments. Mycological culture on Lowenstein medium demonstrated Actinomadurella pelletiere. Treatment with cotrimoxazole for 8 months led to significant regression of the lesions.

Discussion: The mycetoma described in this report posed a diagnostic challenge because of its unusual scalp location and especially its tumoral or pseudo-cystic presentation. This clinical form of mycetoma must be taken into account for diagnosis in any patient from endemic areas.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Actinomycetales / isolation & purification*
  • Actinomycetales Infections / complications
  • Actinomycetales Infections / diagnosis*
  • Actinomycetales Infections / drug therapy
  • Adult
  • Anti-Infective Agents / therapeutic use
  • Female
  • Humans
  • Mycetoma / diagnosis*
  • Mycetoma / drug therapy
  • Mycetoma / microbiology
  • Scalp Dermatoses / diagnosis*
  • Scalp Dermatoses / drug therapy
  • Scalp Dermatoses / microbiology
  • Time Factors
  • Treatment Outcome
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Anti-Infective Agents
  • Trimethoprim, Sulfamethoxazole Drug Combination