Targeting serotonin synthesis to treat irritable bowel syndrome

Gastroenterology. 2011 Aug;141(2):420-2. doi: 10.1053/j.gastro.2011.06.024. Epub 2011 Jun 22.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Biphenyl Compounds / therapeutic use*
  • Female
  • Humans
  • Hydroxyindoleacetic Acid / urine*
  • Irritable Bowel Syndrome / drug therapy*
  • Male
  • Phenylalanine / analogs & derivatives*
  • Phenylalanine / therapeutic use
  • Serotonin / biosynthesis*
  • Tryptophan Hydroxylase / antagonists & inhibitors*

Substances

  • 2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-methoxybiphenyl-4-yl)ethoxy)-pyrimidin-4-yl)phenyl)propionic acid
  • Biphenyl Compounds
  • Serotonin
  • Phenylalanine
  • Hydroxyindoleacetic Acid
  • Tryptophan Hydroxylase