Abstract
Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacillus / genetics*
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Bacillus / metabolism*
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Chromosome Mapping
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Fermentation
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Frameshift Mutation
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Genome, Bacterial*
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Lactate Dehydrogenases / genetics
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Lactate Dehydrogenases / metabolism
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Lactic Acid / biosynthesis*
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Molecular Sequence Data
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Plasmids
Substances
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Lactic Acid
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Lactate Dehydrogenases
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D-lactate dehydrogenase