A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of DNA-functionalized gold nanoparticles

Chem Commun (Camb). 2011 Aug 14;47(30):8557-9. doi: 10.1039/c1cc12377g. Epub 2011 Jun 27.

Abstract

DNA-functionalized gold nanoparticles are shown to act as a light-scattering switch. Ag(+) ion turns on the switch through the DNA-Au NPs conjugates based on the formation of cytosine-Ag(+)-cytosine base pairs, whereas cysteine turns off the light-scattering signal because it competitively binds to Ag(+).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cysteine / analysis*
  • DNA / chemistry*
  • DNA Probes / chemistry
  • Gold / chemistry*
  • Ions / chemistry
  • Light
  • Metal Nanoparticles / chemistry*
  • Scattering, Radiation
  • Silver / analysis*
  • Spectrophotometry, Ultraviolet / methods*

Substances

  • DNA Probes
  • Ions
  • Silver
  • Gold
  • DNA
  • Cysteine