Abstract
Seventeen flavonoids including one new compound were isolated from Texas bluebonnet (Lupinus texensis), the state flower of Texas. Their structures were determined by extensive nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry analyses. High-performance liquid chromatography analytic method for simultaneous determination of the 17 compounds was established and validated. Eleven isolated flavonoids were first evaluated for their free radical scavenging activity using α,α-diphenyl-β-picrylhydrazyl scavenging assay and they showed activity with EC(50) 48.6-172.5 µg mL(-1).
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Biphenyl Compounds
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Chromatography, High Pressure Liquid
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification*
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Free Radical Scavengers / pharmacology
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Linear Models
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Lupinus / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Picrates
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification*
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Plant Extracts / pharmacology
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Spectrometry, Mass, Electrospray Ionization
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Texas
Substances
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Biphenyl Compounds
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Flavonoids
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Free Radical Scavengers
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Picrates
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Plant Extracts
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1,1-diphenyl-2-picrylhydrazyl