One amino acid change located in the conserved region of the alpha 1 domain specifies the novel HLA-C*07:147 allele

P S Becker; D Fürst; K Recker; J Mytilineos; C Seidl

doi:10.1111/j.1399-0039.2011.01715.x

One amino acid change located in the conserved region of the alpha 1 domain specifies the novel HLA-C*07:147 allele

Tissue Antigens. 2011 Oct;78(4):292-4. doi: 10.1111/j.1399-0039.2011.01715.x. Epub 2011 Jun 27.

Authors

P S Becker¹, D Fürst, K Recker, J Mytilineos, C Seidl

Affiliation

¹ Department of Transplantation Immunology and Immunogenetics, Johann Wolfgang Goethe University Hospital, German Red Cross Blood Donor Service Baden-Württemberg-Hessen, Frankfurt am Main, Germany. [email protected]

PMID: 21707538
DOI: 10.1111/j.1399-0039.2011.01715.x

Abstract

The novel HLA-C allele HLA-C*07:147 contains one nucleotide substitution in exon 2 leading to an amino acid change in the alpha 1 domain from phenylalanine to leucine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles*
Amino Acid Substitution*
HLA-C Antigens / genetics*
Humans
Mutation, Missense*
Protein Structure, Tertiary

Substances

HLA-C Antigens